Martinecz, Antal; Boeree, Martin J.; Diacon, Andreas H.; Dawson, Rodney; Hemez, Colin; Arnoutse, Rob; Abel zur Wiesch, Pia (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-04-13)
Background - Antibiotic treatments are often associated with a late slowdown in bacterial killing. This separates the killing of bacteria into at least two distinct phases: a quick phase followed by a slower phase, the latter of which is linked to treatment success. Current mechanistic explanations for the in vitro slowdown are either antibiotic persistence or heteroresistance. Persistence is defined ...